A 60-year-old man from Florida has been taken to hospital in Newcastle with "serious injuries", after his bike collided with a car on the A66.
The accident happened at Threlkeld, near Keswick.
The driver of the car was uninjured in the accident.
Motorists are asked to follow the diversions in place.
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Mainly dry. Light rain out of thicker cloud over hills. Breezy at times and cooler than average
A look ahead at the forecast for the Border region.
Pictures from the commemoration marking the centenary of the Quintinshill rail disaster, which killed more than 200 people, is underway.