The A5086 partially blocked due to flooding between A595 / Howbank Road (Egremont) and A66 (Cockermouth Roundabout, Cockermouth).
Motorists are being advised to approach the road with care.
There are various stretches of the road affected as well as a number of minor routes through Frizington, Wath Brow, and Cleator Moor.
More top news
A writer from Carlisle has won the UK's most prestigious poetry award, the T. S. Eliot Prize.
ITV Border has learnt police officers are being called on "an almost daily basis" to help transfer patients from west Cumbria to Carlisle.
A teenage driver who led police on a high-speed chase through a residential area of Carlisle has been sentenced.