Two lanes are closed northbound on the A74 (M) between junctions 21 and 20, due to a crash involving two lorries.
One of the lorries struck the central reservation, and it is expected that the two lanes will be closed for some time.
Traffic heading towards Lockerbie is also being affected.
More top news
Paul Spence's death at a scrapyard in Carlisle is being investigated by police and the Health and Safety Executive.
Hundreds of people took part in activities to mark the start of the Chinese New Year.
Emma Jesson brings you Saturday night's forecast