A report by the Muscular Dystrophy Campaign "Trailblazers" found 75% of those questioned felt they had no choice but to shop online due to a lack of physical access.
One of those who took part in the survey was David Gale from Carlisle.
He's encouraging high street businesses to do more to support shoppers with disabilities and stop ignoring them.
Kim Inglis went to meet him.
More top news
Carlisle is expected to be a hotly contested seat, and on May 7 the vote could be a benchmark for the rest of the country.
It'll be built at the site of the old Robinson's Brewery in Ulverston.
A new display at Dumfries Museum celebrates the Scots who fought, and sometimes died, for their country.