This is the scene on the A66 at Threlkeld in the Lake District, where two vehicles collided.
Two adults and a boy aged 10 are seriously ill.
Two other children have also been taken to hospital.
More top news
Our political editor Peter MacMahon looks at the significance of today's meeting between May and Sturgeon
Images released of two men following break-in
Theresa May insists that Brexit must come before Indyref2