Two adults and a boy aged 10 have been airlifted to the Royal Victoria Infirmary in Newcastle after an horrific crash in the Lake District this morning.
All three have serious injuries.
Two other children have been taken to hospital by road ambulance. Their injuries are less serious.
The crash, involving two vehicles, happened on the A66 at Threlkeld, near Keswick, shortly before 10am on Saturday.
The two adults are believed to be the children's parents.
More top news
On the first day of the meteorological Autumn - what will the weather have in store?
The First Minister will introduce standardised tests in primary schools, and a number of other bills in the next Parliament session.
Vern Cotter has announced the Scotland squad for the 2015 Rugby World Cup, and three players from the Scottish Borders are included.