Marcy Dixon from Carlisle had to have a blood transfusion at just seven-weeks-old in order to undergo a heart operation.
The process had to be repeated last year when she was four-years-old.
Now, she's fit and healthy and has a special message for everyone who gives blood:
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The historic event always takes place on the last Friday in July.
Early enquiries suggest the men may have taken the drug Blue Valium. Two of them remain in hospital with breathing problems.
More than 8,000 people are expected to attend over the three day event, which starts at 7pm tonight.