Traders in Dumfries say 18 businesses have closed in the past four months.
This week Scottish Enterprise announced it was starting a service in Dumfries and Galloway to support retailers.
But traders in the town say that without urgent help, the situation is likely to get worse.
I think it's very close to becoming a ghost town, as are all small towns in Scotland now.
They are all on the edge of disaster. We are not doing enough to make it easier to shop in the town centre.
We are standing in a big pedestrianised area, people like their cars to go shopping, but they can't take their car anywhere near our town centre because there's just no access.
More top news
Kerrie brings you Sunday night's forecast
Brightening up Sunday. Temperatures and humidity rising. Cloudier skies with showery rain into Monday into Tuesday
Kerrie brings you Saturday night's forecast