It is being billed as the biggest transformation of children's health care for the region in over a century.
Today was the launch of a charity campaign to raise half of the 40 million pounds needed to make the changes.
These improvements will benefit hundreds of children and parents. Gemma Wright has a son, Rio, who suffers with breathing problems as well as issues with his sight and skin.
The charity Make It Better hopes the local community will help raise a large chunk of the cash. The money will see improvements to wards with 48 single rooms to offer families more space and privacy. Key departments will be brought closer together to reduce journey times.
They will also be a new outpatients department. Better parking facilities. And a range of play areas - so brothers and sisters visiting, have somewhere to stretch their legs.
The government is putting up the rest of the cash needed to make the project happen. Building work is expected to start next Spring.