On the day MPs have been discussing a plan for a blanket ban on legal highs, Calendar can reveal that more than half of 18 to 24 year olds have taken them.
In the second of our special reports on the substances being openly sold online and on our high streets, Grace Melody-Gardner spoke to a mother whose son's curiosity put his life in danger.
An aid worker from Doncaster working in West Africa has said that more needs to be done at a local level to help stop the spread of Ebola. Ian Bray spoke to Calendar News from Liberia about the challenges charities are facing.
The charity Dreamflight has taken a group of children with serious illness and disabilities to Orlando in Florida. Forget VIPs, they're known as VICs - 'Very Important Children'. Our reporter Lauren Hall went with them to find out how they got on.
Emergency services and trading standards in Lincolnshire say they are extremely concerned about a huge rise in the number of cases involving so-called legal highs being reported to police.
From 2012 to 2013 the number of incidents reported to the Force went up by more than 600 per cent. Raids have now been carried out on shops selling the substances.
Grace Melody-Gardner reports:
A woman from East Yorkshire has had rare surgery - using her ankle to create a new knee jointRead the full story ›
Dog owners are warning that popular walking spots in their area are being littered with poisoned sweetsRead the full story ›
A Keighley man is due to appear before magistrates today after being charged last night with murder and attempted murder.
Grzegorz Dzierzak, 34, from Chapel Lane, Keighley will appear at Bradford Magistrates Court charged with the murder of Edgaras Masliuskas, 23, in Keighley.
He has also been charged with the attempted murder of another 23-year-old man. The charges follow an incident in the early hours of Sunday October 26 in Chapel Street in which both victims received stab wounds.
The 23-year-old man remains in hospital where his condition is serious but improving.
The number of incidents involving so-called legal highs in Lincolnshire has increased by more than six hundred percent over a 12 month period.
Calendar has seen figures showing the rise - which emergency services and trading standards have expressed concern over.
A woman from Hessle's had rare surgery - using her ankle to create a new knee joint.
Jordon Moody had her thigh removed after being diagnosed with bone cancer for the second time. Surgeons reattached the bottom of her leg - with the foot turned back to front - to create the new knee.
Campaigners fighting to save the region's only children's heart surgery unit say two far-reaching reports vindicate their claims that the unit is, and always has been - safe.
The reports out today looked at the treatment of 14 patients over a 10 year period at the Leeds General Infirmary, along with the temporary suspension of operations last year. And they concluded that the unit is well-run and in a position to go from strength to strength. Tina Gelder reports