Bridgewater Place junction will be closed from 4pm this afternoon, as winds of up to 60 mph are expected to hit.
The council say anyone working in the area may want to consider staggering journeys home and people should be aware that pedestrians as well as traffic will be diverted from the junction of Water Lane, Victoria Road and Neville Street.
It is expected that the diversions will be in place until the early hours of the morning, sometime between 2am-4am.
Video Credit: Lee Collings Photography
Severe winds have been knocking over pedestrians around Bridgewater Place in Leeds.
The road was closed to cars around Yorkshire's tallest building this morning.
It comes days after a coroner said action needed to be taken after a lorry blew over outside the building, crushing a man to death in 2011.
Thousands of drivers in Leeds have faced huge delays this morning, because of road closures in the city centre.
The Council chose to close the road past the Bridgewater Place tower - the tallest building in Yorkshire - after predictions wind speeds in the area could reach 75mph.
Surrounding roads are still congested as drivers try to find alternative routes.
Two years after a man was crushed by a lorry that was blown over, the owners of Yorkshire's tallest building say they will start working on a solution to cut wind speeds around the site.
An inquest heard how Dr Edward Slaney died after the HGV toppled onto the pavement outside Bridgewater Place in Leeds City Centre. Today the hearing resumed - after it was dramatically halted last year.