Speaking to ITV News from the family home in Coulsdon in south London, Meredith Kercher's sister Stephanie said:
We welcome the news in the sense that we hope to find the answers. We are never going to be happy about any outcome because we have still lost Meredith but we obviously support the decision and hope to get answers from it.
There are still so many unanswered questions, all we have ever wanted to do is do what we can for Meredith and to find out the truth of what happened that night.
Rudy Guede's conviction was on the basis that there was more than one person there so that is something that needs to be looked into.
It was painful to receive the news that the Italian Supreme Court decided to send my case back for revision when the prosecution's theory of my involvement in Meredith's murder has been repeatedly revealed to be completely unfounded and unfair.
I believe that any questions as to my innocence must be examined by an objective investigation and a capable prosecution.
The prosecution responsible for the many discrepancies in their work must be made to answer for them, for Raffaele's sake, my sake, and most especially for the sake of Meredith's family.
Our hearts go out to them. No matter what happens, my family and I will face this continuing legal battle as we always have, confident in the truth and with our heads held high in the face of wrongful accusations and unreasonable adversity.
In a statement, Amanda Knox added that the prosecutors' theory of her involvement in the murder is "completely unfounded and unfair".
No matter what happens, my family and I will face this continuing legal battle as we always have, confident in the truth and with our heads held high in the face of wrongful accusations and unreasonable adversity.