The A65 Main Street is closed in both directions between Long Preston and Cleatop due to a serious accident.Traffic is being diverted using the A682.
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The Tykes beat Millwall 2-1 in the League One play-off final to win their second trophy at Wembley this year.
Goals from Ashley Fletcher and Adam Hammill see Barnsley take a 2-1 lead at half-time at Wembley in their play-off final with Millwall.
There were ugly scenes at Wembley ahead of the League One play-off final as Millwall supporters clashed with police.