The union warned that Rotherham will not be the last hospital to announce cuts as many are struggling to cope with the impact of funding cuts, rising patient numbers and the legacy of Private Finance Initiative debt.
"This is terrible news for patients and for the local community who will lose vital health services. Cutting nursing staff at a time when we have an ageing population and have already lost nearly 6,000 nurses since the ConDems came to power should worry everyone who relies on the NHS in Rotherham. This announcement will be a devastating blow for families in the run-up to Christmas. The jobs market is incredibly tough. People will struggle to find other work.
More top news
Steve Bruce has been accused of trying to "defend the indefensible" over Maynor Figueroa's tackle on Stephen Ireland.
Former Leeds and Sheffield United midfielder Chris Kamara says that people are more willing to report racist incidents in sport.
Five men have been jailed for a total of 22 years for their involvement in a series of ATM ram raids across the region in 2012.