14-year-old Jessica Magee was last seen on Tuesday evening in Balby. She told her mother that she was leaving and had packed some make up and clothes, including her Balby Carr school uniform, and that she would attend school the following day.
Jessica did not attend school the next day and has not been seen or heard from since.
She is described as white, approximately 5ft 4ins tall with long, dark hair.
Police are appealing for anyone with information about where she might be to get in touch.