Bombardier is in competition with three international rivals for the £1 billion contract to build 60 trains for Crossrail's cross London routes.
Today, as she launched the tender process, Transport Secretary Justin Greening said she was "keen to understand and communicate the benefit of this contract the the UK economy."
The Government was heavily criticised when Bombardier lost out to German firm Siemans on a Thameslink rail project, prompting a review of the public procurement process.
The Transport Secretary Justine Greening made references to UK businesses when she announced the process:
A number of outcomes from the Government's review of public procurement have been reflected in this procurement, which could bring opportunities to UK businesses"
"This means bidders will need to set out how they will engage with the wider supply chain and provide opportunities for training, apprenticeships and for small and medium-size businesses within their procurement strategy."
The Derby factory received a boost last week with a visit from Prince Charles, with workers saying they hoped the Royal 'seal of approval' would also help.