Scotland Yard has urged Portuguese authorities to reopen the search for Madeleine McCann as detectives said there were 195 potential leads to finding her alive.
The detective leading the Metropolitan Police review said the case could still be solved before officers released a picture of what she might now look like as a nine-year-old.
Detective Chief Inspector Andy Redwood said he believed her disappearance was a stranger abduction, as he said there were 195 "investigative opportunities".
Police refused to say what evidence they had uncovered to suggest Madeleine was alive.
Mr Redwood confirmed that his team had been out to Portugal seven times, including a visit to the family's holiday flat in Praia da Luz.
It will be five years ago next week since the three-year-old went missing.
There have been hundreds of possible sightings of her all over the world since she vanished, but so far they have come to nothing.
The appeal number is 0800 0961011 from within the UK. The number for non-UK residents is +44 2071580 126. Anyone who does not wish to speak directly with police can contact Crimestoppers on 0800 555 111.
More on the police investigation at ITV news.
Alison Mackenzie has the full report: