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The A38 Suffolk Street Queensway Southbound is closed because of an accident involving a lorry at B4127 Holloway Head / Smallbrook Queensway (Holloway Circus).
There is congestion to A38 St Chads Queensway / B4114 New Town Row / B4114 James Watt Queensway (Lancaster Circus).
London Midland train services between Shrewsbury and Wolverhampton have been disrupted and replacement bus services are running because of an "operating incident" between Shrewsbury and Wellington.
There is no estimate for when a normal service is likely to resume.
Disruption is expected on some East Midlands Trains services this weekend because of improvement work on the main line into St Pancras International.
Network Rail is improving the track and overhead lines between St Pancras and Kentish Town meaning East Midlands Trains will not be able to travel further than West Hampstead and some trains will terminate at Luton on Saturday and Sunday.
One lane closed due to accident on M1 Northbound between J24A A50 (Derby/Stoke/East Midlands Airport) and J25 A52 Brian Clough Way (Nottingham / Derby).
Slow traffic due to earlier accident on M6 Northbound between J13 A449 (Stafford South) and J14 A34 / A5013 / A5013 Creswell Grove (Stafford North). All lanes have been re-opened.
A456 in both directions closed due to serious accident near the Tenbury Community Hospital off Forresters Road.
One lane blocked due to ladders in the road on M69 Southbound between J1 A5 (Hinckley / Nuneaton) and M6 J2 / A46 (Coventry).
One lane blocked and queueing traffic due to broken down vehicle on M6 Southbound between J13 A449 (Stafford South) and J12 A5 (Gailey).
Slow traffic and one lane closed due to accident and recovery work on M42 Southbound between J2 A441 (Alvechurch / Redditch) and J1 A38 / B4096 (Bromsgrove).
Latest ITV News reports
As temperatures dip below freezing this weekend, Leicester's gritting lorries have been out and about on the roads.
Here's a full list of the roads affected by the wet and windy weather - with up to an inch of rain expected to fall today.