The President of an American biosciences company has applauded the University of Leicester for its work into ground-breaking identification of new treatment for infectious hospital bugs.
Phil Young, from AmpliPhi Biosciences Corporation, also commented on his excitement at working with Dr Martha Clokie, the lead scientist at the university.
We are very excited about this partnership with Dr Clokie and the University of Leicester. Phage-based therapy has the potential to revolutionise the way C diff infections are treated in the clinic, in compliance with the regulatory frameworks already in place. We firmly believe that this collaboration may result in a treatment that could benefit patients, clinicians and health-care organisations alike.
– Phil Young, CEO and President of AmpliPhi Biosciences Corporation
The lead scientist in research to identify viruses that can combat an infectious bug in hospitals has said the current goal for the project is to create a pill or capsule, to deliver the antibiotic alternative directly into patients.
Dr Martha Clokie from the University of Leicester has been part of research into the viruses that fight against suberbug, Clostridium difficile.
She believes capsules containing the bacteriophages would be the best way to attack the illness.
C diff bacteria primarily affect our digestive system… C diff infections can cause severe diarrhoea, vomiting and dehydration. Collectively, these symptoms can prove life-threatening, particularly in elderly patients.
(Traditional antibiotics)... are routinely used to treat C diff infections in the UK, but resistance to both is rapidly increasing. What is worse, in addition to killing the C diff bacteria, these antibiotics also destroy the 'good' gut bacteria, in turn increasing the potential for relapse or new infections. Consequently, C diff infections pose a substantial healthcare burden for the NHS and a significant drain on its resources.
The key advantage of using phages over antibiotics lies in their specificity. A phage will infect and kill only a specific strain/species of bacteria.