Both carriageways of the A1 between Grantham and Newark are closed after a fatal crash between a lorry and a van.
Nottinghamshire Police say it happened near Long Bennington around 5.30 am on the 19th June, both vehicles caught fire, filling carriageways with 'large plumes of smoke'.
Occupants of the van were pronounced dead at the scene though police say it is not yet been confirmed how many people were killed.
The southbound carriageway is expected to re-open before noon but the northbound carriageway is expected to remain closed for the majority of the day.
Diversions are in place at the junctions with the A52 and A46, but motorists are being asked to avoid the area where possible.