A 39-year-old man from Leicester has died in a major accident on the M25 in Essex.
Four other people are being treated in hospital.
The crash is believed to have involved a lorry crossing the central reservation, and part of the motorway will be closed for the foreseeable future.
"The vehicles involved were a Peugeot car, a Scania lorry, a DAF artic, a Mercedes lorry and a Romanian lorry. The man who died was pronounced dead at the scene and his body has now been taken to the mortuary at Princess Alexandra Hospital in Harlow.
"He is believed to be a 39-year-old man from Leicester.
"Four other people remain in hospital receiving treatment for injuries which are not believed to be serious.
"The M25 currently remains shut between junctions 25 and 27 while clean up and repair work continue.
"Police have now released the scene to the Highways Agency."
Some 11 people "will be interviewed as witnesses" by the police searching for missing Madeleine McCann, Good Morning Britain heard.
British and Portuguese "men and women" are expected to be quizzed by the police over what happened to the missing youngster.
Detectives are investigating an attack in Leicester that has left a man in a critical condition in hospital.
The 19-year-old victim was assaulted on Market Place at 12.20pm yesterday, beside Yorkshire Bank and Santander Bank.
A short while later he was involved in a further incident in nearby Belgrave Gate.
The victim suffered a very serious head injury and needed an emergency operation at University Hospital, Coventry and he is now in a critical condition.
He is white, and was wearing an orange sweatshirt. Police are appealing for witnesses.
“At this time of day there would have been a lot of people in the Market Place area who may have seen the initial incident, or who may have seen the man in the orange top.
"I would ask them to contact me - no matter how small the information it may prove vital to finding out what happened to this man.”
A witness appeal has been launched following the deaths of two teenage girls in a crash with a bus.
A blue Peugeot 206 was involved in the accident with a single decker bus at 1.25pm on Friday on Empingham Lane near Tickencote.
Anna and Anastasia, who were both boarders at Oakham School, were pronounced dead at the scene.
Two teenage girls who died in a horror car crash with a bus have been named in tributes on social media.Read the full story ›
British police are expected to arrive in Portugal today to question a number of people over the disappearance of Madeleine McCann.
The three-year-old, from Rothley in Leicestershire, went missing from a holiday apartment in Praia da Luz in Portugal in 2007.
Scotland Yard detectives will be expected to interview Robert Murat, who was arrested as part of the Portuguese police investigation into her disappearance at the time.
As well as questioning seven suspects, four other people will be interviewed as potential witnesses.
British police travelled to Portugal over the summer and spent eight days searching three areas of Praia da Luz, but found no new evidence.
Police are due to arrive in Portugal today to interview seven suspects over the disappearance of Madeleine McCann.
Madeleine, from Rothley in Leicestershire, went missing from a holiday apartment in Praia da Luz in Portugal in 2007, nine days before her fourth birthday.
Scotland Yard detectives will be expected to interview Robert Murat - who was arrested as part of the Portugese police investigation into her disappearance in 2007.
Mr Murat has always denied any involvement.
As well as the seven suspects, four others will be interviewed as potential witnesses.
British officers spent eight days searching three areas of Praia da Luz this summer but found no new evidence.
Police are appealing for witness after two teenage girls died when their car crashed into a bus in Rutland.
The crash happened at 1.25pm yesterday lunchtime on Empingham Lane near Tickencote, and involved a blue Peugeot 206 and a single decker bus.
The 17 and an 18-year-olds were both pronounced dead at the scene. ITV News Central understands they were both boarding students at private Oakham School.
The driver and eight passengers in the bus received superficial injuries.
Officers from East Midlands Serious Collision Investigation Unit are investigating.
Detective Constable Pete Davies said:
“The car was travelling along Empingham Lane towards Empingham and the bus was travelling in the opposite direction towards Tickencote when the collision occurred.
“We would like to speak to anyone who may have witnessed the collision or saw either vehicle beforehand to contact us."
Anyone with information is asked to call police on the 101 number.
A fatal crash involving a car and a bus in Rutland killed two teenage girls who were studying at Oakham School ITV News Central has learned.
The crash happened on Empingham Lane near Tickencote at 1.25pm yesterday lunchtime.
Oakham School Girls Killed after car and bus crash between Tickencote and Empingham, Rutland, R.I.P https://t.co/vfAcsmQ9DF
Sources have told ITV News the two girls in their final year at Oakham School both died instantly. They were boarders at the independent school, which teaches around 1000 students between the ages of 10 and 18.
Leicestershire Police have refused to comment on the incident, but a Twitter account run by Oakham Police did Tweet about the incident yesterday, describing it as a 'tough shift' for those officers involved.
Tough shift for many at the local policing unit...serious road collision thanks to @leicsrpu for coming over and dealing. Joe
A spokesperson for Oakham School has told ITV News Central the force has advised them not to release any information.
However a source told ITV News Central that a service was held for those in the boarding school last night, and a fundraising dinner planned for this evening has been cancelled as a mark of respect.
The spokeswoman did describe the incident as an:
Incredibly sad time for our community
One parent paid tribute to those killed on Twitter, describing the crash as 'utterly devastating'. They also sent their prayers for the parents of the two girls who died.
A number of people who were on the bus received minor injuries.
Empingham Lane near Rutland Water was closed yesterday, but has now reopened.
A 19 year-old man from Leicester has been jailed for eighteen months after he fired a gun into the air and pointed it at members of the public during a fight.
CCTV shows Zunaid Bobat, from Cavendish Road, firing the gun and pointing it at people on Gallowtree Gate at around 6.30am on 22 March.
Fortunately no one was injured in this incident, however it could have been so much worse.
He was found guilty of possession of a firearm or imitation firearm, with intent to cause fear or unlawful violence.
Through the extensive CCTV network we were able to trace Bobat from Vestry House through the city centre to Gallowtree Gate, where the firearm discharge took place.
We were then able to follow him back to Vestry House, via Lee Circle car park where he had dumped his clothing.
He was arrested later in the day from Vestry House.
Without this CCTV coverage we would not have been able to secure this conviction.