Some passengers on board flight MH17 may have remained conscious during the short period between it being struck by a missile and crashing to the ground.
However, Dutch investigators said it was likely that those on board were "barely able to comprehend the situation in which they found themselves" during the 60-90 seconds in which the plane came down.
The report said passengers would have been exposed to "factors that had an extreme impact on the body" such as the noise of the impact, the abrupt change in speed of the aircraft, the decompression and extreme cold.
As a result, it found that passengers were unlikely to have "performed conscious actions" during the short period, and no photographs or text messages were found on devices such as mobile phones aboard the plane.
All 298 people on board were killed in the disaster.
Dutch investigators have released an animated report showing the route MH17 took up to the moment the airliner disappeared from radar.
The Dutch Safety Board have questioned why civilian airlines were flying over an area of armed conflict.
A Dutch investigator said: "Nobody gave any thought to the possible threat to civil aviation."
Dutch investigators have criticised both the Ukrainian authorities and airlines for flying over the country during a period of conflict in which flight MH17 crashed.
The Dutch Safety Board said airlines flying over the area should have recognised the dangers of flying over the east of the country amid fighting between Ukrainian loyalists and pro-Russian separatists.
The investigators also said Ukraine should have closed airspace in the region before the plane was brought down.
A Russian-made missile warhead struck MH17 above its cockpit, causing it to crash in eastern Ukraine, an investigation by Dutch authorities has found.
At a press conference, the Dutch Safety Board said the flight was shot down from Eastern Ukraine.
The rebuilt fuselage of flight MH17 has been displayed as a report into the cause of the disaster is set to be published by Dutch investigators.
ITV News Correspondent Emma Murphy reports that the remains of the outer body show shrapnel puncture marks centred around the cockpit.
It is understood that the report will state that a Russian-made Buk missile struck the plane above and to the left of the cockpit, causing it to come down in eastern Ukraine last year.
Ukraine should already have closed air space over a conflict area where MH17 came down in July last year, a report into the disaster is expected to say.
The International Civil Aviation Organisation is also looking into new regulations on war-zone flying in the wake of the disaster, ITV News understands.
A Russian manufacturer has refuted claims that its Buk missiles were the cause of the MH17 air disaster.
ITV News understands that a report released by Dutch investigators will say that a warhead typically associated with the missile system hit the plane, causing it to come down over eastern Ukraine in July last year.
However, in a press conference shortly before the report's release, the Almaz-Antey manufacturer insisted its own results "completely disprove" such a conclusion.
Citing an "experiment" carried out by the state-controlled company, general director Yan Novikov claimed that if the plane was indeed shot down by a missile, it would have come from the Zaroshenske, a village Russia says was under the control of the Ukrainian government at the time.
A report into the MH17 air crash will show that the plane was hit by a warhead of the type used on a Buk missile system, ITV News understands.
It is understood that the report by Dutch investigators will also show the missile hit above and to the left side of the cockpit, and those on board did not feel anything on its impact.
Buk missiles are developed in Russia, and have allegedly been used by pro-Russian rebels in eastern Ukraine, where the plane came down.
The missile's manufacturer has already challenged investigators' view of events leading to the disaster.
The final report into what caused flight MH17 to crash will be published today.
A total of 298 people, including 10 Brits, were killed when the Malaysia Airlines plane was seemingly shot down over Ukraine last July.
Among the Britons killed were 20-year-old Richard Mayne from Leicester and Loughborough University student Ben Pocock.