The meeting between British and Portuguese police over the Madeleine McCann case is routine and there are no plans for any imminent arrests.
Met Police want to speak to a number of men about a large number phone calls they made in the area on the night the child vanished.
The Portuguese inquiry into the disappearance of Madeleine McCann has been reopened amid new leads in the case.
At a press conference following a European Council summit, Mr Cameron said:
"I have spoken to the Portuguese prime minister before. I didn't speak to him this council about this issue but obviously I'm pleased that the Metropolitan Police have taken this case forward and they have been working with the Portuguese.
"I stand ready, if ever required to, to speak to the Portuguese prime minister or other Portuguese authorities again but I haven't been asked to by the Metropolitan Police and they seem to be making some progress."
Scotland Yard has so far written three international letters of request to the Portuguese, covering 41 priority areas and including 287 separate requests.
Detective Chief Inspector Andy Redwood revealed earlier this week that the force are looking for a lone intruder who sexually abused five British girls during a series of break-ins in the Algarve, Portugal.
David Cameron has said he stands ready to speak to the Portuguese over the investigation into the disappearance of Leicestershire girl Madeleine McCann.
The Prime Minister did not raise the current British inquiry with Portugal's prime minister, Pedro Passos Coelho, during meetings in Brussels but will step in if Scotland Yard asks for help.
It comes after Deputy Assistant Commissioner Martin Hewitt expressed frustration at the speed of the legal system through which British police have to ask for Portuguese assistance with their inquiry.
Former Metropolitan Police Chief, Dai Davies, has been speaking to ITV News Central about the latest developments in the case of Madeleine McCann's disappearance.
Davies, who used to be Head of Royal Protection, before he retired says these latest developments are welcomed, but hopes science can support the links.
Police are currently looking a similarities between Madeleine's disappearance in 2007 and twelve separate incidents between 2004 and 2010 where a lone intruder has appeared in the bedrooms of British girls on holiday on the Algarve.
Last night, following a new television appeal, 250 calls were received by investigating officers by members of the public.
Police investigating the disappearance of Leicestershire girl Madeleine McCann have taken more than 250 calls from members of the public after a second Crimewatch appeal, last night.
Officers revealed they were looking for a lone intruder who sexually abused four girls during a series of break-ins at holiday homes in the Algarve, Portugal between 2004 and 2010.
DCI Andy Redwood said last night: “While some of these offences have been in the public domain before, following our appeal in October three more were reported to us as a direct result of that appeal. One of those reports we believe is the first in the potential series."
Police say they will now review the information they have received
British police investigating the disappearance of Madeleine McCann today revealed they are looking for a 'lone intruder'.
The man is believed to have sexually abused four girls during a series of break-ins at holiday homes in the Algarve, Portugal between 2004 and 2010.
Madeleine, from Rothley in Leicestershire, went missing in May 2007.
Jane Hesketh has the full story.
The Metropolitan Police's DCI Andy Redwood said that binmen were heard by witnesses in two sex attack cases police believe could be linked to the 2007 disappearance of Madeleine McCann, in a new appeal for information today.
The Metropolitan Police have released a computer generated image of the distinctive burgundy long sleeve top worn by a man that detectives investigating the disappearance of Madeleine McCann are looking for.
Detectives investigating the disappearance of Madeleine McCann have released details about the man they are looking for:
- Dark, tanned skin, with short dark unkept hair
- Speaks in English with a foreign accent
- Slow, slurred speech and a calm demeanour
- An unusual smell – either tobacco or aftershave
- Two families say he was wearing a distinctive burgundy round-neck top with a white circle on the back
Detectives investigating the disappearance of Madeleine McCann are looking for a lone intruder who sexually abused five girls during break-ins at holiday homes
Detective Chief Inspector Andy Redwood said tracing the tanned, dark-haired man man, said to have "an unhealthy interest in young white female children", is one of his priority lines of inquiry.
The man is suspected of breaking in to 12 properties where British families were staying in the Algarve, Portugal between 2004 and 2010.
In the incidents girls aged between seven and 10 years of age were sexually assaulted.
These attacks happened between 2004 and 2006, before Madeleine vanished in 2007.
His team currently have 38 people classed as "persons of interest" to the inquiry, and are also sifting through details of 530 known sex offenders whose whereabouts they cannot account for.
Of those 59 are classed as high priority, and some of those are British.
Police investigating the disappearance of Madeleine McCann are looking for a lone intruder who sexually abused four girls during a series of break-ins at holiday homes in the Algarve, Portugal between 2004 and 2010, Detective Chief Inspector Andy Redwood said today