Police are tonight still questioning three people over the disappearance of Coventry mother Nicola Payne.
The 18-year-old was last seen in the city in December 1991.
Earlier today two men both aged 49 were arrested at their homes in the Bell Green and Stoke areas of Coventry on suspicion of her abduction and murder.
A 51-year-old woman from the Bell Green area was also arrested on suspicion of perverting the course of justice.
Two men from Coventry have been arrested on suspicion of the abduction and murder of Nicola Payne. Read a timeline of the case.Read the full story ›
Two men have been arrested in Coventry on suspicion of the abduction and murder of Nicola Payne, who went missing 22 years ago.
The two men are both aged 49 and were arrested at 8am this morning in the Bell Green and Stoke areas of Coventry.
A 51-year-old woman was also arrested at the Bell Green address on suspicion of perverting the course of justice.
All three suspects are being questioned by detectives at police stations in the West Midlands.
Nicola disappeared in Coventry on 14 December 1991 and the mother-of-one has not been seen since.
Two men have been arrested on suspicion of the abduction and murder of Nicola Payne, who went missing from Coventry 22 years ago.
A "number" of new lines of enquiry have emerged from a re-appeal for information following a forensic breakthrough in the case of a young mother who has been missing for 22 years.
Nicola Payne was last seen leaving her boyfriend's house in Coventry, setting off on the short journey to her parents' house.
But she never arrived - and, as tomorrow marks the 22nd anniversary of her disappearance, police are hoping that cutting-edge forensic technology will finally cast light on the mystery.
Det Insp Martin Slevin said:
We have received a number of calls relating to Nicola’s disappearance and some have given us new and interesting lines of inquiry to follow up.
We are asking for anyone who hasn’t phoned us yet and who has information to come forward. We are determined to find what happened to Nicola and bring closure to her family.
The parents of missing mother Nicola Payne have welcomed news of a forensic breakthrough in her disappearance, saying they are desperate for closure.
John and Marilyn Payne said they have suffered for 22 years not knowing what became of their 18-year-old daughter, who vanished as she made the short journey home from her boyfriend's house.
In a statement today, John and Marilyn Payne also urged anyone who may know anything about her disappearance to contact police as soon as possible.
We, as a family, welcome any breakthrough that may lead us to finding out what happened to Nicola and bringing us some closure and we fully support their investigations.
It has been nearly 22 years since our daughter Nicola went missing. For many years we have suffered not knowing what has happened to her.
We await the result of these forensic tests and ask if there is anyone who has information that will assist the police to please make contact with officers.
Officers involved in the reopened case of missing mother Nicola Payne, who went missing 22 years ago, say they still need anyone with information to come forward.
The message comes as police reveal they may have made a key forensic breakthrough in trying to discover what happened to the 18-year-old more than two decades ago.
Det Insp Martin Slevin said the 21st anniversary appeal last December turned up several fresh lines of inquiry which have been developed over the past 12 months.
The re-appeal focused on two men spotted standing by a blue Ford Capri parked near Nicola's route home on the day she disappeared.
The 21st anniversary appeal into the disappearance of missing mother Nicola Payne focused on two men spotted near the area she was last seen.
Nicola, who was 18 at the time, left her boyfriend's home in Winston Avenue, Wood End, Coventry, at around midday on December 14, 1991, heading to her parents' home in nearby Woodway Close. She is thought to have walked across a patch of land known as the Black Pad - but never arrived.
Two men were spotted standing near a blue Ford Capri nearby that day. They have never been identified.
Both men were white, one around 6ft and wearing a brown leather jacket, and the other 6ft 3ins and thin, with short brown hair parted to the side, and wearing a brown bomber-style jacket with a hoodie and light blue denim jeans.
They were standing next to the Capri, which was parked by the Cardinal Wiseman school playing fields, which borders the Black Pad. It is thought to be a 1980 or V-reg, with a black spoiler and dirty wheels.
Police today said they are unable to confirm whether the new evidence relates to the two men.
Detectives investigating the 22-year-old disappearance of young Coventry mother Nicola Payne have described the latest evidence in the case as "exciting".
The new developments have come about after a 21st anniversary re-appeal last December.
Det Insp Martin Slevin, who is leading the inquiry, said forensic analysis would be carried out in the coming weeks - and vowed to explore every avenue to try to solve the mystery.
A dedicated team of detectives continues to work on the case of Nicola’s disappearance. Over the past year we have gone right back to the start of the investigation and reviewed every piece of information that has come into the inquiry.
As a result we have submitted some items for cutting edge forensic testing and other enquiries are currently ongoing.
We will always act on any new information to find out what happened to Nicola and bring some closure to her family, who are being kept informed of all new developments
The inquiry is constantly reviewed and it is hoped that this breakthrough may bring us some answers as to what happened to Nicola that day.
The latest developments are exciting and we will not give up exploring every opportunity to solve this case.
New forensic evidence has been uncovered in the 22-year-old mysterious disappearance of Coventry mother Nicola Payne.
Police say they have sent a number of items off for analysis - and they hope the results could provide answers over what happened.
Saturday marks the 22-year anniversary of Nicola's disappearance.
The 18-year-old, who had a seven-month-old son, was last seen leaving her boyfriend's home in Winston Avenue, Wood End at around midday on Saturday 14 December 1991, to walk the short distance to her parents’ home in Woodway Close.
But she never arrived.
Police launched a fresh appeal for information to mark the 21st anniversary of her going missing - and the new evidence has come as a result of their efforts.
Read: The Case of Nicola Payne