Junior doctors have walked out for a second 24-hour strike amid the ongoing bitter row with the government over pay and conditions.
Thousands of operations, check-ups and tests have been cancelled as a result of the industrial action, which started at 8am.
Junior doctors at the Queen Elizabeth Hospital in Birmingham and the Royal Derby Hospital were among those on strike across the Midlands.
The M1 Southbound is closed at J15A A43 / A5123 (Towcester / Northampton Services) and there is congestion back to J16 A45 / A4500 (Daventry) after a "serious crash".
Traffic is being diverted on the A43 on the back of the Rothersthorpe services. The road is likely to be shut for most of the rush hour.
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Junior doctors have been told what to do if a trust declares a major emergency during the strike.
During the last junior doctors' strike, Sandwell Hospital in West Bromwich declared a level 4 incident and told its junior doctors they must attend work.
As you know when we last took industrial action there was some confusion about when trusts could call junior doctors back into work.
In addition to the legal advice we took at that time we now have a joint letter signed by Sir Bruce Keogh of NHS England and the BMA's Mark Porter setting out the protocol should a major unpredictable incident occur.
According to the letter, junior doctors can be requested to work if:
- There is both "exception and sustained deterioration in performance such as to endanger patient safety and cannot be managed through the deployment of the hospital’s senior hospital doctors and the junior doctors providing emergency care".
- The Trust must make a formal request to NHS England, who will then contact the BMA.
Thousands of junior doctors across England have gone on strike and only emergency care will be provided during the 24-hour walkout.
The A5 Northbound is closed in Towcester, Northamptonshire because of a collapsed manhole between A43 and Duncote.
Thousands of junior doctors across England are going on strike after last-ditch talks failed to reach an agreement.
Junior doctors - which refers to all doctors below consultant level - will only provide emergency care from 8am Wednesday morning in the 24-hour walkout.
It is the second day of strike action by the British Medical Association (BMA) in a bitter dispute with the Government over a new contract.
It is understood the BMA put forward a proposal that would have seen doctors' basic pay rise by about half the 11% offered by ministers in return for Saturday not to be treated as a normal working day.
The union argued it would have been cost neutral, meaning the Government would not pay any more than the £5bn currently spent on junior doctor salaries.
But it is thought the Government blocked that deal.
The Independent Police Complaints Commission has started its investigation into the police response to the missing persons report for a 20-year-old woman who was killed in Northampton last month.
India Chipchase was reported as missing by her family on January 30 and her body was found the following day.
A 51-year-old man has since been charged with her murder.
The IPCC investigation will initially look into the actions and decisions made by police dealing with the missing persons report.
"My thoughts are with India's family at this difficult time.
We will be undertaking a thorough investigation into how police responded to the concerns for India following her disappearance."
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