The woman was found injured in Cauldon Road in Shelton, close to the junction with Boughey Road, at around 21:30 yesterday evening.
She died at the scene. Another man was taken to hospital with leg injuries.
A man was arrested shortly afterwards and is being questioned by Staffordshire Police.
The woman has not been formally identified and her next of kin are being traced.
Reports of one lane blocked and very slow traffic due to accident on M6 Northbound from J16 A500 (Stoke-On-Trent / Crewe) to Sandbach Services.
A woman from Stoke-on-Trent is aiming to set a Guinness World Record by running a marathon in high heels.
Natalie Eckert has a few months to train. She is attempting the record next April.
HS2 Ltd's Executive Chairman David Higgins is expected to make significant announcements about HS2 in Leeds this morning.
Mr Higgins will be presenting his report on the project, and will give recommendations on the second phase, which runs from Birmingham to Leeds and goes through the East Midlands.
It is believed he will announce that a suggested route for the high-speed service through Stoke-on-Trent will be dumped in favour of a hub at Crewe, on the western arm of the 'Y'-shaped northern route.
It is rumoured that he will recommend that plans for a high-speed rail link in Nottinghamshire should be moved to Derbyshire. It was originally proposed that the HS2 station should be at Toton Sidings, but there may be new plans to try to link HS2 to existing rail lines serving Nottingham and Derby.
Steven Bazell from Stoke-on-Trent has broken a new world record for completing the Birmingham half-marathon in fancy dress.
Steven ran the race to raise money for Birmingham Children's Hospital.
His son was born with a congenital heart condition and has undergone two life-saving operations.
Stoke woman prepares to move into a glass box in Tesco'sRead the full story ›
A van driver suffered a severe head injury after crashing into a wall in Staffordshire this morning.
The woman, aged 42, was anaesthetised at the scene while emergency crews worked to free her from the van.
She was then taken to the major trauma centre at University Hospital North Staffordshire for further treatment.
Paramedics were called to Draycott Lane in Tean, Stoke-on-Trent, shortly after 5.30am and found the van had left the road and smashed into a wall.
More than £250,000 worth of cannabis has been seized from an abandoned building in Staffordshire.
Police were called to the building in Queen Street in Burslem, Stoke-on-Trent, yesterday morning after CCTV operators reported two men acting suspiciously nearby.
Building inspectors were called to ensure it was safe for officers to enter the crumbling property - but after being given the all-clear, teams found around 1,700 plants spread across eight rooms.
Lee Tuong, aged 30, has been charged with producing cannabis and will appear before Newcastle Magistrates Court tomorrow.
A 58-year-old man, who was also arrested at the scene, has been bailed pending further inquiries.
More than 100 large bags of compost were also seized, and will be donated to community groups for use in gardening projects. Anyone interested can call Sgt Mark Churton at Burslem police station on 101.
Police believe a body found in woodland in Stoke-on-Trent is that of missing man Paul Woodcock.
He had been reported missing from his home in Meir on 9th August.
The body was found in woods close to football pitches off Whittle Road in Meir yesterday morning.
A post-mortem examination proved inconclusive and further tests will be carried out over the coming weeks to establish the cause of death.
The two men arrested in connection with the death have been released without charge.