All lanes of the M1 are now open after the accident involving five lorries between Junction 25 and 26.
The motorway is still congested with journeys between junctions 24 and 25 taking 40 minutes.
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Despite receiving treatment at the scene, the man was pronounced dead shortly after.
Cloud will largely clear this evening, although with variable cover and few light showers over the Derbyshire hills.
The rain will clear during the evening so the rest of the night will be dry and mild with long clear periods.