Kate McCann, has welcomed the launch of two initiatives to help find missing children.
Tonight she attended a Downing Street reception to mark the introduction of a new Europe-wide hotline and the relaunch of an official website with information about Britain's missing children.
She said that the 116000 missing children phone number was a "lifeline" for families like hers.
Our correspondent Gareth Owen has revisited Praia da Luz, five years since the disappearance of Madeleine McCann.
A timeline of events on how the investigation into Madeleine McCann's disappearance has elapsed over the 5 years since she went missing.
The parents of Madeleine McCann have spoken about the investigation into their daughters disappearance in a TV interview.