Residents living in the Lydford Road area of Alfreton are being urged by police to close their windows and doors as a precaution whilst emergency services tackle a fire.
Forty firefighters are currently at the scene trying to get the fire under control.
The fire, which broke out on an industrial estate at 12.10pm today has caused concern due to the smoke and possible harmful chemicals it may contain.
Lydford Road has been closed whilst firefighters tackle the blaze, the cause is not yet known.
More top news
A clear and chilly night, with sunshine tomorrow.
Clear overnight then sunny during Sunday. Light winds.
Tributes have been paid to a "talented" 17-year-old amateur boxer who died after collapsing in the ring.