They serve more than four million people across the region, and now two of those people have said a very special thank-you to East Midlands Ambulance Service for their life-saving skills.
Simon Bakewell from Leicester suffered a heart attack while out walking with his family, just weeks after having a heart transplant. His heart stopped beating - but an off-duty crew managed to help bring him back to life. Callum Watkinson reports.
More top news
A blast of late winter weather has brought snow flurries to many parts of the Midlands.
A primary school which closed after travellers moved on to nearby land has remained shut for a second day.
The wife of an alleged extremist is due to appear in court accused of helping her husband buy a knife in a plot to carry out an attack.