They serve more than four million people across the region, and now two of those people have said a very special thank-you to East Midlands Ambulance Service for their life-saving skills.
Simon Bakewell from Leicester suffered a heart attack while out walking with his family, just weeks after having a heart transplant. His heart stopped beating - but an off-duty crew managed to help bring him back to life. Callum Watkinson reports.
More top news
The government has announced proposals recommending making full use of existing airport capacity while a third runway is built at Heathrow.
Armed police have been called in to reports of a man with a firearm at a home in Warwickshire.
Fire crews are tackling a fire that has broken on a lorry on the M1 in Derbyshire. All lanes have been closed northbound at junction 29a.