The emergency services were called to a house fire overnight on Holtlands Drive in Alvaston.
The fire service received the call just after 2:30 this morning.
One man was taken to hospital where he later died. All the other people in the house were accounted for.
Firefighters left the scene just before 6.00 but will return later today to carry out further investigations.
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Ambrose Parsons is said to have left the QE Hospital earlier today (Saturday 17 February) still wearing a green hospital gown.
Staying largely dry with clear spells, leading to frost for some.
There may be a few spots of rain during the evening, however it will be largely dry overnight with clear spells.