The emergency services were called to a house fire overnight on Holtlands Drive in Alvaston.
The fire service received the call just after 2:30 this morning.
One man was taken to hospital where he later died. All the other people in the house were accounted for.
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Cloudy and windy in the East. Cloudy and mild, with patchy rain in West.
Most places dry overnight. Cloudier and windier during Sunday.
Cloudy and mild on Sunday, risk patchy rain in west.