The Government hailed the court's decision on the cases it won as a "landmark victory" and said the loss on the compensation case would "not affect the HS2 construction timetable in any way".
Rail Minister Simon Burns said: "This is a major landmark victory for HS2 and the future of Britain. The judge has categorically given the green light for the Government to press ahead without delay in building a high-speed railway from London to Birmingham, Manchester and Leeds."
An influential group of MPs says the DfT has failed to present 'a convincing strategic case' for HS2.
Campaigners say they hope to put plans for HS2 through the Midlands back to square one as they prepare to go to the High Court tomorrow.
Campaigners from HS2 Action Alliance are heading to London tomorrow to take on the Government at the Court of Appeal.