The crash between a Police car and a Peugeot 206 happened on Broxtowe Lane in Aslpey in Nottingham at around 14:00 this afternoon (March 31).
A 12-year-old boy and a man have been taken to hospital.
The police officer was responding to a 999 call, and was not injured in the collision.
More top news
Cloudy with further outbreaks of rain, which are likely to become heavy at first. Staying generally dry after midnight.
Outbreaks of rain will slowly clear all but the far south by morning, where it could turn briefly heavy for a time.
Police in Nottingham are growing increasingly concerned for an 18-year-old girl who has been missing for four days.