Gary Barlow, Chris Evans, James May and Brian Cox will drive through the Midlands today in a pink Rolls Royce raising money for Breast Cancer Care.
The challenge will see them driving from Land's End to John O'Groats in a bespoke pink Rolls Royce Ghost.
They want to try and raise £1 million in 24 hours.
The four celebrities will stop off in Birmingham as part of their trip to meet breast cancer sufferers from the Midlands.
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"Street cruising in the city has escalated recently posing a real threat to innocent, law-abiding motorists and pedestrians."
It will be a grey start to Monday with patchy rain and drizzle moving in from the south.
Perhaps locally bright at first, but increasing cloud will bring periods of light rain from the south. Winds generally light.