The march has been organised by a community group, with the support of local MPs and Stafford Borough Council.
It comes after the hospital has been placed in administration.
The rally is aimed at saving services such as the Accident and Emergency department, intensive care and maternity units.
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Fine and dry with good spells of sunshine this weekend.
Dry and rather warm in sunny spells on Friday.
Police have named a man who died after a knife attack in the St Ann's area of Nottingham as 21-year-old Reuben Morris-Laing.