The march has been organised by a community group, with the support of local MPs and Stafford Borough Council.
It comes after the hospital has been placed in administration.
The rally is aimed at saving services such as the Accident and Emergency department, intensive care and maternity units.
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Further snow showers are expected to continue through the morning, easing somewhat during the afternoon.
Strong, bitterly cold winds, with sunny intervals and scattered snow showers.
Old Market Square in Nottingham was a blaze of orange, green and white as hundreds brave the blizzard-like conditions.