Birmingham will play a key role in a world-first Cancer Research UK study.
Experts from Birmingham hospitals will track how lung tumours develop and evolve in real time as patients receive treatment.
The research, which is one of the largest studies of lung cancer patients globally, will examine how the disease mutates and becomes resistant to treatments.
The study will take nine years and will cost £14 million.
– Professor Gary Middleton, research leader
Success in treating lung cancer has been difficult to achieve but we're hoping to change that.
The first step to improving cancer diagnosis and treatment is to understand more about the disease and how it changes over time. We plan to harness new sequencing technologies to trace the genetic evolution of cancer over the course of the disease. Our research will help explain why lung cancer is difficult to treat, and steer a path towards saving more lives.