Shrewsbury's Flax Mill Maltings was "phenomenally important" in the creation of the world's skyscrapers, a site project manager said.
Flax Mill Project Manager Elizabeth Perkins added that the world's first iron framed building was created out of "necessity" from "revolutionary thinking".
"All over the country there were terrible fires that killed lots of people, so they were looking for a solution," Ms Perkins said.
She added: "No one else would have gone on and taken that leap that then went into steal and steal frame, that then went into the technology that went into skyscrapers today.
"It's a seminal moment, and it just changed people's attitude, it's a moment in history that just transformed things."
Today it was announced that the Flax Mill Maltings in Shrewsbury had been awarded a lottery grant of £12.8 million to regenerate the site.
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The building in question, Cygnet Wharf development, is currently being constructed.