The A5 in Northamptonshire is closed in both directions between the A45 / High Street, Weedon Bec, and the A43 at Towcester due to ice on the road.
There will be no access until gritters have treated the surface.
As temperatures dip below freezing this weekend, Leicester's gritting lorries have been out and about on the roads.
Here's a full list of the roads affected by the wet and windy weather - with up to an inch of rain expected to fall today.
Dozens of roads are closed across the Midlands this morning due to flooding, including a number of main A routes.