Nottinghamshire Police are concerned for the state-of-mind of 31-year-old Vanessa Firth.
The mother-of-one, from Netherton Road, Manton, has not been seen since 6:45pm on Wednesday.
Officers and relatives have searched the local area, including Hannah Park and Library Gardens where she enjoys visiting, but she is nowhere to be found.
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The woman in her thirties had to be cut out of her car and then airlifted to hospital after a collision in Powick.
Some warm spells of sunshine will develop during the day. However, an isolated heavy shower is possible towards the west.
Sunny spells likely for the afternoon. And feeling pleasantly warm away from the coast. Light easterly winds will keep coasts cooler.