The A5127 Birmingham Road in Lichfield is closed in both directions between Knowle Lane and Fosseway / Shortbutts Lane after a lorry hit a railway bridge.
The road is likely to stay closed into this afternoon while recovery work takes place.
As temperatures dip below freezing this weekend, Leicester's gritting lorries have been out and about on the roads.
Here's a full list of the roads affected by the wet and windy weather - with up to an inch of rain expected to fall today.
Dozens of roads are closed across the Midlands this morning due to flooding, including a number of main A routes.