The A14 in Northamptonshire is closed westbound between junctions 3 and 2 after a three-vehicle crash.
The air ambulance is on scene, and fire crews are working to free a trapped motorist.
Police have advised one lane will open once the air ambulance has lifted off.
As temperatures dip below freezing this weekend, Leicester's gritting lorries have been out and about on the roads.
Here's a full list of the roads affected by the wet and windy weather - with up to an inch of rain expected to fall today.
Dozens of roads are closed across the Midlands this morning due to flooding, including a number of main A routes.