Martin Solomon has cancer for the second time in his short life.
The 20-year-old from Sale desperately needs to find a donor match for a life-saving stem cell transplant.
This week, "spit" clinics are being held across Greater Manchester.
Potential donors can sign up to the register in minutes.
Paula Solomon, Martin's mother is asking people across the region to "spare just ten minutes of their life, which could give Martin the rest of his."
She said: "It is a simple test and the next steps can be discussed should they be a match.
"Martin has beaten this once and we need to do all we can to help him beat it again.
"It could be anyone of us in need of a donation and it only takes one person to be that match that for someone. There could be no greater gift than giving the chance of life.
"If you are not a match for martin you could be a match for one of the many others like Martin still waiting for a stem cell donor."
Local spit clinics are being hosted by Greater Manchester West Mental Health NHS Foundation Trust on:
Wednesday January 9 2013 between 12noon and 8.30pm at the Waterdale Restaurant on the Prestwich Hospital site
Thursday January 10 2013 between 12.30pm and 8.30pm at the Meadowbrook ECT Suite at Salford Royal Hospital
Friday January 11 2013 between 12.30pm and 8.30pm at the Bolton ECT Suite at Royal Bolton Hospital
Saturday January 12 2013 between 11am and 4pm at Park House (next to Trafford Hospital)
The clinics are open to anyone aged 16 to 30 years old and who weighs over eight stone. No appointment is necessary.
The test is a simple spit test to see if someone is a match and only takes a few minutes.