Abdul Hamid Chaudhry of Chorlton was sentenced to 20 months in prison. He pleaded guilty at an earlier hearing to conspiracy to sell counterfeit goods and money laundering.
Mohammed Kamran Chaudhry of Prestwich was sentenced to two years in prison. He pleaded guilty at an earlier hearing to conspiracy to sell counterfeit goods and money laundering.
Mohammed Basit Chaudhry of Chorlton was sentenced to three years four months in prison. He pleaded guilty at an earlier hearing to possessing a class B drug with intent and money laundering.
Shahnuz Akhtar Chaudhry of Chorlton has been sentenced to ten weeks in prison. She pleaded guilty at an earlier hearing to five counts of mortgage fraud.
During the course of the investigation officers recovered counterfeit clothing worth £250,000 and over seven kilograms of cannabis with a street value of around £70,000.
Since 2009, a series of warrants have been executed at the business and home addresses of the Chaudhry family.
During the investigation further companies run by the family were identified and officers from Trading Standards confirmed that counterfeit goods had previously been seized.
Detective Inspector Chris Mossop, of the Serious Crime Division, said: "The Chaudhry empire was a vast operation that netted them untold profits.
"They lived lavish lifestyles off the back of it while many people have been struggling to make ends meet in difficult financial times.
"They may have briefly enjoyed the trappings of so-called success, such as expensive watches and luxury holidays, but they are all distant memories to them now as they languish in jail.
"I hope today's sentence reminds people that we will not rest until we have brought criminals to justice, no matter how sophisticated or successful you think you are."