Mr Henning, who's 47, was kidnapped soon after crossing into Syria with an aid convoy in December last year. The Government says it won't negotiate with I-S and won't pay ransoms. But in the meantime, Mr Henning's friends say hostages from other countries have been released.
Dr Sameela Islam-Zulfiqar travelled to Syria with Alan Hemming and was with him shortly before he went missing. She's made a direct appeal to the Islamic State to release him.
The wife of kidnapped aid worked Alan Henning says the Islamic state have so far ignored her pleas for his release.
It's over a week since they released a video threatening to kill the Salford taxi driver .
Mrs Henning has pleaded with the militants to "see it in their hearts" to release him but has so far received no response.
Should the north west be given greater political power to decide it's own future ?
Just one of the questions being asked at the start of the Labour Party conference which has opened in Manchester .
Our Political correspondent Alison Mackenzie reports.
The wife of Islamic State hostage Alan Henning has appealed for the release of a "peaceful and selfless man".
ITV News has obtained previously unseen pictures of the 47 year old, hours before he was kidnapped in Syria last December.
The wife of British hostage Alan Henning has pleaded with Islamic State militants not to "allow the world to see a man like Alan dying".
Ina statement released through the Foreign Office, Mr Henning's wife Barbara said she has sent messages to IS urging them to release her husband but has received no response.
I am Barbara Henning the wife of Alan Henning.
Alan was taken prisoner last December and is being held by the Islamic State.
Alan is a peaceful, selfless man who left his family and his job as a taxi driver in the UK to drive in a convoy all the way to Syria with his Muslim colleagues and friends to help those most in need.
When he was taken he was driving an ambulance full of food and water to be handed out to anyone in need.
His purpose for being there was no more and no less. This was an act of sheer compassion.
I cannot see how it could assist any State's cause to allow the world to see a man like Alan dying.
I have been trying to communicate with the Islamic State and the people holding Alan. I have sent some really important messages but they have not been responded to.
I pray that the people holding Alan respond to my messages and contact me before it is too late.
When they hear this message I implore the people of the Islamic State to see it in their hearts to release my husband Alan Henning.
The wife of British hostage Alan Henning has called on "the people of the Islamic State to see it in their hearts to release my husband", describing him as a "peaceful, selfless man".
Controversial Muslim scholars have joined calls for the release of a Salford aid worker Alan Henning who's being held by extremists in Syria.
They describe the threats against him as "totally prohibited" under Islamic law.
Labour activists will gather today ahead of the start of the party's annual conference following Scotland's decision to reject independence.
Ed Miliband arrived in Manchester as Prime Minister David Cameron announced plans to ensure English MPs were the only politicians allowed to vote on issues that affect England.
But Mr Miliband said he wants a national debate on the issue of constitutional reform.
Any moves to restrict Scottish MPs' votes on English matters could undermine any future Labour Government.
The Labour event is due to begin with a women's conference as Deputy Leader Harriet Harman, shadow home secretary Yvette Cooper and shadow equalities minister Gloria De Piero all address activists.