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Gary Barlow, Chris Evans, James May and Brian Cox have set off from Lands End in a pink Rolls Royce raising money for Breast Cancer Care.
The challenge will see them driving from Land's End to John O'Groats in a bespoke pink Rolls Royce Ghost.
They want to try and raise £1 million in 24 hours.
The Olympic cyclist Shanaze Reade is hoping to start her 2013 campaign with a world title.
Shanaze who's from Crewe is among the favourites for gold at the BMX World Cup meeting in Manchester this weekend. It's the first time the event has been held in the north west.
Mike Hall reports on Lancashire's hopes for the new County Championship season, which gets underway tomorrow. Promotion back to Division One is the top priority.
Macclesfield Town have sacked Steve King and Pablo Asensio with immediate effect. Youth team manager John Askey will take charge of the side. It comes after they lost 3-1 to Grimsby last night.
Latest ITV News reports
British light-middleweight Brian Rose took a step towards elite level with a battling 12th-round stoppage of Joachim Alcine in Blackpool
Tyson Fury recovered from a knockdown to knock out Steve Cunningham in the seventh round of their heavyweight clash at Madison Square Garden