Captain Steven Gerrard and defender Daniel Agger will miss Liverpool's final two matches of the season, starting with Sunday`s game at Fulham.
Gerrard will have a shoulder operation this weekend while the Denmark centre-back will have injections in his back as part of a long-planned rehabilitation programme.
Luis Suarez is suspended, Joe Allen is sidelined after shoulder surgery, Martin Kelly continues his recovery from a knee operation.
Provisional squad: Reina, Johnson, Carragher, Skrtel, Enrique, Lucas, Henderson, Downing, Coutinho, Borini, Sturridge, Jones, Wisdom, Coates, Suso, Assaidi, Shelvey, Coady.
Manchester United striker Danny Welbeck will miss Sunday's Premier League encounter with Chelsea due to a knee injury.
Manager Sir Alex Ferguson confirmed this morning that the 22-year-old will not be involved in the Old Trafford game, when Paul Scholes is expected to return.
"Danny is out for Sunday," Ferguson said. "We hope to have Paul Scholes on the bench to get him back in the fray."