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Fans can enter the competition by donating £5 which will go towards Stand Up To Cancer, a joint fundraising campaign led by Cancer Research UK and Channel 4. The prize includes return flights to Miami, accommodation, tickets to the final show of the Where We Are tour and a chance to meet the band on October 5. The winner will also receive signed merchandise.
Harry Styles from Cheshire and the other band members say they've been working with the charity Stand Up to Cancer for a while and they wanted to offer a very special prize to raise money for research.
If you want to enter the competition then you can click here to find all the details.