British champion Peter Kennaugh has abandoned the Tour de France, because of illness.
Kennaugh, from the Isle of Man, was part of the team which supported Froome to the 2013 title.
The 26-year-old was 146th at the start of the 201-kilometres route from Bourg de Peage to Gap, almost two and a half hours behind Froome.
Kennaugh, who won London 2012 Olympic gold in the team pursuit on the track, successfully retained his British title on June 28 in Lincoln.
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Olympic champion Sir Bradley Wiggins is optimistic of success in the Road World Championships time-trial in Ponferrada on Wednesday.
Wiggins finished second to Germany's Tony Martin, the Olympic silver medallist, in Florence last year but is confident the 47.1-kilometre route favours his attributes this time around.
"I'm in better shape than last year," the 34-year-old Wiggins told BBC Sport.
"It's quite mountainous and suits me more than Tony. Every year I think this might be the year but you never know. That's why I like it."
Wiggins is joined in the race by Commonwealth Games champion Alex Dowsett.
The Londoner beat Dowsett to the British title in June and won a short Tour of Britain time-trial last weekend.
"This year's course is a lot different to last year's, which was long and flat," added Wiggins, who did not ride the Glasgow 2014 time-trial.
"You have to think more on this course. There's no room for error.
"You need to have enough in the tank for the end. It's challenging, a true test of the time trial."
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Sir Bradley Wiggins has confirmed that he will not be riding the Tour de France if the defending champion Chris Froome holds his form up to the start of the race in Leeds on 5 July.
The 2012 winner said today: “The team is focused around Chris Froome who has got a chance of winning his second Tour and it’s been decided to base the team around him.”
“I’m gutted,” Wiggins added. “I’ve worked hard all year for this, I went to California and won that, I feel I’m in the form I was in 2012, but I understand that cycling is a team sport and at the end of the day it’s about the team winning, at the end of the day it’s about Chris winning.”
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Manxman Peter Kennaugh has been named in Team Sky's line-up for the 2014 Giro d'Italia, which begins in Belfast on May 9.
The 24-year-old, from Douglas, was a key member of the Team Sky squad which helped Chris Froome to Tour de France glory in 2013.
The nine-strong team for the first Grand Tour of the season will also feature Italian riders Dario Cataldo and Salvatore Puccio, Ben Swift, Edvald Boasson Hagen, Bernhard Eisel, Sebastian Henao and Kanstantsin Siutsou.
On confirming the team line-up Team Principal, Sir Dave Brailsford, said: “We’ve brought together an exciting squad and we can’t wait, not only for the start in Northern Ireland, but to perform in front of our Italian fans.”