Photographs from the scene of what emergency services say was a "tragic fire," show just how intense the blaze was.
Flames ripped through the house in Withington, Manchester in the early hours of this morning. Two people, a man and a woman, were killed.
Four children, aged 10 to 17, are being treated in hospital alongside another man.
Investigators have increased the size of the area that is sealed off around the house, on Parsonage Road, while they try to determine the cause of the fire.
A house fire which has killed two people, and put five others in hospital, is a "tragic incident" according to police.
Medics say they are treating four children, the youngest aged 10, and a man. Firefighters were called to the property in Withington, Manchester at 2.21am this morning.
This is a tragic incident and we are working work closely with Greater Manchester Fire and Rescue to establish exactly how this fire started.
We want to speak to anyone who may have witnessed the fire, or were in the area in the hours before the fire.
Two people have been killed, and five others injured, after a house fire described by firefighters as "serious and tragic."
Emergency crews were called to the blaze on Parsonage Rd in Withington, at 2.21am this morning. Medics are treating three girls, and a boy, all aged between 10 and 17. A man, whose age has not been made public, is in a serious condition.
Investigators are trying to find out what caused the fire. The area is expected to be sealed off for several hours.
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Firefighters are tonight at the scene of an explosion at a cafe in North Manchester.
Emergency services say it was caused by a cooking accident at the Emerald Cafe in Harpurhey.
One person has been taken to hospital with burns. A large section of Rochdale Road is closed.
- Video from MEN Syndication
Demolition of Oldham's fire-ravaged of Maple Mill has started.
Around 40 firefighters continue to tackle pockets of fire inside the mill, using aerial appliances to put water on the fire from above.
Residents from around 20 properties in Cardwell Street remain unable to return home due to the unsafe structure of the building.
The demolition process could take around three days.
"Firefighters continue to work hard tackling the fire and our priority is getting people back into their homes as soon as we can.
"Later into the demolition process we will know more about the structure of the building and about timescales for residents to return home."
A major fire at a mill in Oldham has been burning throughout the day, and now the fire service say people may have been sleeping inside.
Dozens of firefighters have been at the scene in Oldham and around a hundred homes have been evacuated as a major incident was declared.
Part of the building, Maple Mill, has collapsed and residents have been reporting thick smoke and ash
Tim Scott has been there throughout the day, we'll be live with him after this report:
Residents near Maple Mill in Oldham are being reminded to keep windows and doors closed, as smoke continues to linger in the town after last night's huge fire.
The fire at the four-storey mill burned throughout the night, and was tackled by more than 80 firefighters at its height.
More than 100 homes have been evacuated. It's still not clear when people will be able to return to their homes.
Our main priority is to get people back into their homes asap but we genuinely do not know when that will be please stay tuned for updates
More than 100 homes have been evacuated as a serious fire continues to burn at a mill near Oldham.
Greater Manchester Fire Service have declared a major incident at Maple Mill on Cardwell Street. Residents in the nearby Fitton Hill area of Oldham are being told to keep windows and doors closed.
People who've been asked to leave their homes have been taken to the nearby Honeywell Centre.
The fire broke out just before 4am this morning. Around 80 firefighters are still at the scene tackling the fire.
Parts of the building are thought to have collapsed and the whole building is engulfed by the fire.
More than 60 firefighters in Oldham are tackling a fire at a paper mill.Read the full story ›